Langerhans cell histiocytosis of the bone
نویسندگان
چکیده
of LCH remains unknown. According to molecular study, LCH is not a disease of the epidermal Langerhans cells, but rather one of the myeloid dendritic cells with mononuclear phagocyte dysregulation. The clinical signs and symptoms of LCH vary depending on the organs and extent of involvement. LCH is diagnosed based on pathologic and immunohistochemical evaluation. Histologic features are not predictive of the clinical outcome. Tumor cells are positive for CD1a and CD207 (langerin). Birbeck granules are demonstrated by electron microscopy.
منابع مشابه
Langerhans cell histiocytosis
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عنوان ژورنال:
دوره 29 شماره
صفحات -
تاریخ انتشار 2017